A Clinical Assessment of Changes in Cell Mediated Immune Response Induced by Geriforte

INTRODUCTION "Geriforte" a geriatric tonic, widely used in this country has been recently reported to induce a state of non-specific increased resistance (SNIR) in animals during stress and was found to prevent various deleterious effects like gastric ulcers, adrenal hyperplasia etc. caused by stress (Singh et al., 1978). This drug was also found to prevent urethane induced lung-adenomas in mice and to cause a marked increase in total lymphocyte count, which by increasing the immune response of the animals might have been responsible for prevention of carcinogenesis (Singh et al., 1980). Besides, it also has anti-viral activity against live-vaccinia virus which, may be again because of its immunostimulant effects (Singh et al., 1981). Considering the above facts, it was thought fit to evaluate its immuno-modulator activity in human subjects through this study.